Brief Summary in Lay Language
The objective of this study is to determine the proportion of people in the general population of Heidelberg and the Rhein-Neckar region with antibodies against the coronavirus.
Brief Summary in Scientific Language
The primary objective of this study is to estimate the age-group specific prevalence of antibodies to SARS-CoV-2 among the general population of Heidelberg and the Rhein-Neckar region. In total 1500 persons from five age-groups will be randomly selected from the population registers. Study participants will be tested for antibodies at three different time points: one study visit will take place during the current epidemic, one post-epidemic and one between these two timepoints. A questionnaire will be administered at each study visit to collect information about symptoms and potential risk factors for SARS-CoV-2 infection.
More information here: link
Study Overview
Study name | Serial cross-sectional seroprevalence study of SARS-CoV-2 infection during and post-epidemic periods in Heidelberg and the Rhein-Neckar region, Germany |
Project | SARS-CoV-2 seroprevalence study |
Sources of Monetary or Material Support | SAP (Systeme, Anwendungen, Produkte in der Datenverarbeitung) |
Region(s) | Germany |
Location(s) | Heidelberg and the Rhein-Neckar Kreis (16 municipalities in total) |
Primary outcome | Seroprevalence for SARS-CoV-2, stratified by age over time |
Research Question | The age-group specific prevalence of cross-reactive antibodies to SARS-CoV-2 among the general population of Heidelberg and the Rhein-Neckar region (RNR) in Germany |
Diagnostic test(s) used |
|
Antibody class(es) | IgG, IgM |
Study population N | 1500 |
Total population in the area | ~700,000 |
Principal Investigator | Claudia Denkinger , University Hospital Heidelberg, Division of Tropical Medicine , Claudia.Denkinger@uni-heidelberg.de |
Team members |
|
Period | 2020-07 till 2020-10 |
Study start | 2020-05 |
First results expected | 2020-12 |
Study metadata
{
"abbreviation": "SARS-CoV-2 seroprevalence study",
"draft": false,
"iscjklanguage": false,
"lastmod": "2020-07-28T13:25:06+02:00",
"logo_url": "/img/uploads/hd_trop.png",
"project_url": null,
"recruitment": {
"country": [
"Germany"
],
"group": "General population",
"location": [
{
"latitude": 49.4137373,
"longitude": 8.6594131,
"place_name": "Heidelberg and the Rhein-Neckar Kreis (16 municipalities in total)"
}
],
"type": "Random selection"
},
"results": {
"doi_preprint": null
},
"study_dates": {
"sample_end": "2020-10",
"sample_start": "2020-07",
"study_first_results": "2020-12",
"study_start": "2020-05"
},
"study_info": {
"diagnostic_test": [
{
"address": null,
"antibody_classes": null,
"company": null,
"product": "ELISA"
},
{
"address": null,
"antibody_classes": null,
"company": null,
"product": "Neutralization Assay"
}
],
"funding_sources": "SAP (Systeme, Anwendungen, Produkte in der Datenverarbeitung)",
"primary_outcomes": "Seroprevalence for SARS-CoV-2, stratified by age over time",
"research_question": "The age-group specific prevalence of cross-reactive antibodies to SARS-CoV-2 among the general population of Heidelberg and the Rhein-Neckar region (RNR) in Germany",
"tested_antibody_classes": [
"IgG",
"IgM"
]
},
"study_numbers": {
"population": "~700,000",
"study_population": 1500
},
"study_pi": {
"email": "Claudia.Denkinger@uni-heidelberg.de",
"institution": "University Hospital Heidelberg, Division of Tropical Medicine",
"name": "Claudia Denkinger"
},
"team": [
{
"email": "Claudia.Denkinger@uni-heidelberg.de",
"institution": "University Hospital Heidelberg, Division of Tropical Medicine",
"name": "Claudia Denkinger",
"position": "Section Director",
"role": "Principal Investigator",
"title": "Dr. med."
},
{
"email": "ivonne.morales@uni-heidelberg.de, kerstin.rosenberger@uni-heidelberg.de",
"institution": "University Hospital Heidelberg, Division of Tropical Medicine",
"name": "Ivonne Morales, Kerstin Rosenberger",
"position": "Epidemiologists",
"role": "Principal Investigator",
"title": "Dr. rer. nat., Dr. sc. hum."
}
],
"title": "Serial cross-sectional seroprevalence study of SARS-CoV-2 infection during and post-epidemic periods in Heidelberg and the Rhein-Neckar region, Germany"
}